The common side effects of oxymetholone include depression , lethargy , headache , swelling , rapid weight gain , priapism , changes in skin color, urination problems, nausea , vomiting , stomach pain (if taken on an empty stomach), loss of appetite , jaundice , breast swelling in men, feeling restless or excited, insomnia , and diarrhea .  In women, side effects also include acne , changes in menstrual periods , voice deepening , hair growth on the chin or chest , pattern hair loss , enlarged clitoris , and changes in sex drive .   Because of its 17α-alkylated structure, oxymetholone is hepatotoxic .  Long term use of the drug can cause a variety of serious ailments, including hepatitis , liver cancer , and cirrhosis ; therefore periodic liver function tests are recommended for those taking oxymetholone. 
The side effects of Anadrol can include liver damage as this steroid is highly hepatotoxic. The use of this steroid will increase liver enzyme values; you should not supplement if your liver isn’t healthy. While liver enzyme values will increase, this does not mean damage has occurred, but it is an indicator of stress that could lead to damage. If liver damage is to be avoided excess alcohol consumption must be avoided. Avoiding all alcohol isn’t a bad idea. The individual should also avoid all over the counter (OTC) medications when possible. Many OTC meds are hepatotoxic, in some cases, more so than many anabolic steroids. OTC meds should be limited to when only absolutely necessary. The individual should also ensure he does not supplement with any other hepatotoxic anabolic steroids, specifically C17-alpha alkylated (C17-aa) steroids when supplementing with Anadrol. There should also be at minimum six weeks of no C17-aa steroid use after Anadrol use and total use should be limited to 4-6 weeks. If the individual can follow these rules, while enzyme values will increase with use, they should return to normal after use is discontinued and no damage will be done.