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It has been reported that the inhibition caused by Methenolone Enanthate (Primobolan Depot) is lesser than that of Deca or testosterone, this is because of the fact that the CNS activities are low, lesser transformation to DHT, and shortage of aromatization to estrogen. Contrasting with Deca, its metabolic activities are not disengaged by 5a-reductase and there are no harm or dangers for skin and hair from this steroid. Nonetheless, when this steroid is used individually for normal dosage, the production of natural testosterone and DHT are inhibited, this can progress and make the skin better if no other anabolic steroids are used with it.
Metenolone , or methenolone , also known as methylandrostenolone , is a synthetic and orally active anabolic–androgenic steroid (AAS) and a derivative of dihydrotestosterone (DHT) which itself was never marketed.      Metenolone itself is not used as an AAS and the drug is instead supplied in ester prodrug form as metenolone acetate for oral administration and as metenolone enanthate for depot intramuscular injection .   Metenolone esters are no longer widely used medically but do remain available in some countries.