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In 1974, the US FDA began the drug review monograph process for "over-the-counter (OTC) topical antimicrobial products," including triclosan and triclocarban. The advisory panel first met on June 29, 1972, and the agency published its proposed rule on Sept 13, 1974. The initial rule applied to, “OTC products containing antimicrobial ingredients for topical human use, which includes soaps, surgical scrubs, skin washes, skin cleansers, first aid preparations and additional products defined by the panel.” [74] The proposed rule lists dozens of products that were already on the market at the time and the firms that produced them.

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